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Signal and propeptide processing of human tissue plasminogen activator: Activity of a pro-tPA derivative

✍ Scribed by David T. Berg; Brian W. Grinnell


Book ID
115764508
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
704 KB
Volume
179
Category
Article
ISSN
0006-291X

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✍ Christiane KΓΆhne; Adriana Johnson; Sabrina Tom; David H. Peers; Richard L. Gehan πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 422 KB πŸ‘ 2 views

Strategies that prevent the attachment of N-linked carbohydrates to nascent glycoproteins often impair intracellular transport and secretion. In the present study, we describe a method to rescue the intracellular transport and secretion of glycoproteins mutagenized to delete N-linked glycosylation s