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Signal and adaptational changes in gene expression during cardiac overload

✍ Scribed by Brigitte Chevalier; Francine Callens; Danièle Charlemagne; Claude Delcayre; Anne Marie Lompré; Lionel Lelièvre; Jean Jacques Mercadier; Jean Marie Moalic; Pascale Mansier; Lydie Rappaport; Jane Lyse Samuel; Ketty Schwartz; Bernard Swynghedauw

Book ID
118916785
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
620 KB
Volume
21
Category
Article
ISSN
0022-2828

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To clarify the pathogenesis of hepatic iron toxicity, we investigated the effect of chronic dietary iron overload on the expression of several genes in rat liver. After 10 wk of iron treatment, when only minor histological features of liver damage were appreciable, the level of pro-a.JI)-collagen mR