Sigma-assistance, an unrecognized factor in organic reactivity

✍ Scribed by J. W. Verhoeven

• Book ID: 104588223
• Publisher: Elsevier Science
• Year: 2010
• Tongue: English
• Weight: 145 KB
• Volume: 99
• Category: Article
• ISSN: 0165-0513
• DOI: 10.1002/recl.19800990412

✦ Synopsis

Abstract

A simple perturbational frontier molecular orbital description with inclusion of sigma electrons is presented for bifunctional intramolecular reactivity. This description readily accounts for the preferred formation of odd membered rings in (di) radical cyclization and of even membered transition states in intramolecular hydrogen or hydride migration.