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Side-effects of protein kinase inhibitors on ion channels

✍ Scribed by Son, Youn Kyoung; Park, Hongzoo; Firth, Amy L; Park, Won Sun

Book ID
121589337
Publisher
Indian Academy of Sciences
Year
2013
Tongue
English
Weight
310 KB
Volume
38
Category
Article
ISSN
0250-5991

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Modulation of potassium channels by prot
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✍ A. H. Saad; S. S. Kuo; A. C. Koong; G. M. Hahn; A. J. Giaccia πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 661 KB

Exposure of non-excitatory cells to the tyrosine kinase (PTK) inhibitors, genistein, herbimycin A, and tyrphostin, induced at least two families of K f currents. The first, a TEA-insensitive slow-inactivating K + current, is induced within 3 min following treatment with 140 m M genistein or 100 n M