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Side chain substitution reaction of 2-arylsulfinyl and 2-arylsulfonyl intermediates for 1β-methylcarbapenems

✍ Scribed by Kozo Oda; Akira Yoshida

Book ID
104257593
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
178 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

Sulfoxide 5 and sulfone 6 derived from l~l-Methylcarbapenem 4 yielded the precursors of l~-methylcarbapenems by MgBr_,-Et20 mediated C-2 side chain substitution reaction with functionalized mercaptans.

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