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Sickle cell adhesion depends on hemodynamics and endothelial activation

โœ Scribed by Matthew C. Wagner; James R. Eckman; Timothy M. Wick

Book ID
113772548
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
248 KB
Volume
144
Category
Article
ISSN
1532-6543

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Abnormal adhesion of sickle cells to vascular endothelium may be a factor in the initiation of painful vaso-occlusive crisis. The sickle cell population contains an unusually large number of less dense reticulocytes that are known to be more adhesive than mature red cells, but there is contradictory