Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients
β Scribed by Steven H. Itzkowitz; Elana J. Bloom; William A. Kokal; Gunnard Modin; Sen-Itiroh Hakomori; Young S. Kim
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 623 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0008-543X
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Background. Several studies have revealed a correlation between sialosyl Tn antigen (STN) and certain clinicopathologic features of various cancers, and that STN is an independent prognostic factor. However, the clinical significance of the expression of STN in gastric cancer has not been reported.
## Abstract Tumor cells are characterized by specific genetic alterations. When such genetic alterations are identified in body fluid including plasma, regardless of the presence of detectable tumor cells, it shows the existence of freeβcirculating tumorβassociated DNA. The objective of our study w