This experiment investigated the effect of antidepressants on the escape deficit induced by inescapable shock. Following exposure to escapable shock, rats received a single injection of either tricyclic antidepressants (imipramine, desipramine), an atypical antidepressant (nomifensine), or saline. I
β¦ LIBER β¦
Shuttle-box deficits induced by inescapable shocks in rats: Reversal by the beta-adrenoreceptor stimulants clenbuterol and salbutamol
β Scribed by P. Martin; P. Soubrie; P. Simon
- Book ID
- 113220752
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 415 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0091-3057
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The present study was undertaken to investigate the possible involvement of a noradrenergic and opioid mediation of the reversal by tricyclic antidepressants of escape deficits produced by inescapable shock pretreatment. Rats were first exposed to 60 inescapable shocks (15 s duration, 0.8 mA, every