Should we use living donor grafts for patients with hepatocellular carcinoma? ethical considerations
โ Scribed by Elizabeth A. Pomfret; J. Peter A. Lodge; Federico G. Villamil; Mark Siegler
- Book ID
- 102470612
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 170 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1527-6465
- DOI
- 10.1002/lt.22356
No coin nor oath required. For personal study only.
โฆ Synopsis
To arrive at a recommendation, our committee examined the following questions:
- Why is living donation necessary, and is it different for patients with hepatocellular carcinoma (HCC)? 2. What is double equipoise, and how is it affected by the diagnosis of HCC? 3. Is a paired exchange appropriate if one or both recipients have HCC?
Methods
Literature searches were conducted, and additional references were provided by committee members.
Conference calls and e-mail exchanges were used to debate the relevant issues because there is a paucity of relevant published data.
๐ SIMILAR VOLUMES
## Key Points 1. Split liver transplantation for a child and an adult recipient is standard today. Living donor liver transplantation for small children should only be necessary in exceptional situations in a country with a well-organized organ donation program. 2. True split liver transplantation
Liver transplantation is now an acceptable treatment for small hepatocellular carcinomas in the setting of cirrhosis. Larger tumors in cirrhotic livers and unresectable tumors in noncirrhotic livers (including fibrolamellar hepatocellular carcinomas) may also be indications for transplantation. With
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