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Should the cytologic diagnosis of “atypical squamous cells of undetermined significance” be qualified?

✍ Scribed by Anton, Rose C. ;Ramzy, Ibrahim ;Schwartz, Mary R. ;Younes, Pamela ;Chakraborty, Subhendu ;Mody, Dina R.

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
155 KB
Volume
93
Category
Article
ISSN
0008-543X

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The Bethesda System recommends that the diagnosis of "atypical squamous cells of undetermined significance" (ASCUS) be qualified when possible to indicate whether a reactive process, or a squamous intraepithelial lesion (SIL), is favored. In order to evaluate the utility of this recommendation, 308

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## Background: The authors have noted that in cervical cytology specimens from perimenopausal and postmenopausal women, the diagnosis of atypical squamous cells of undetermined significance (asc-us), as defined in the bethesda system, is often not associated with a clinically evident lesion on foll