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Should family members of IBD patients be screened for CARD15/NOD2 mutations?

✍ Scribed by Severine Vermeire; Gert Van Assche; Paul Rutgeerts

Book ID: 112101033
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 43 KB
Volume: 14
Category: Article
ISSN: 1078-0998
DOI: 10.1002/ibd.20587

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Background: Antibodies directed against Saccharomyces cerevisiae (ASCA), perinuclear components of neutrophils (pANCA), and porin protein C of Escherichia coli (anti-OmpC) are reported to be associated with disease phenotype and may be of diagnostic importance in inflammatory bowel disease (IBD). Si