𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Shortening reaction in patients with cerebellar ataxia

✍ Scribed by Dr. Ronald W. Angel

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
678 KB
Volume
11
Category
Article
ISSN
0364-5134

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

During passive extension of the elbow, the triceps muscle normally shows a burst of electromyographic activity. This shortening reaction (SR) is known to be exaggerated in extrapyramidal disease states, but the effects of cerebellar disease are unknown. The SR was measured in both arms of a patient with hemiataxia, the unaffected arm serving as a matched control. In the ataxic arm, the SR was significantly larger and did not show the normal increase during “reinforcement.” In a patient with bilateral ataxia, the SR was grossly exaggerated as compared with the SRs in a group of normal subjects. The present findings indicate an unexpected point of similarity between cerebellar and extrapyramidal disease states, which is discussed in terms of the anatomical connections of the cerebellum and basal ganglia. The techniques used in this work provide a quantitative approach to disorders of movement and muscle tone.

📜 SIMILAR VOLUMES

High-dose piracetam is effective on cere
High-dose piracetam is effective on cerebellar ataxia in patient with cerebellar cortical atrophy
✍ Melih Vural; Sibel Özekmekçi; Hülya Apaydin; Attila Altinel 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB

## Abstract We describe a patient with cerebellar ataxia of degenerative nature who was administered high‐dose piracetam in a single‐blind trial. Piracetam was demonstrated to be highly effective on tandem gait and gait ataxia in daily doses of 60 g. We suggest piracetam has a potential anti‐ataxic

Social economic costs and health-related
Social economic costs and health-related quality of life in patients with degenerative cerebellar ataxia in Spain
✍ Julio López-Bastida; Lilisbeth Perestelo-Pérez; Fernando Montón-álvarez; Pedro S 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 69 KB

## Abstract To determine the economic burden (direct and indirect costs), as well as health‐related quality of life (HRQOL) in patients diagnosed with spinocerebellar ataxia (SCA) in Spain. A cross‐sectional study was carried out on 84 patients with SCA from the Spanish Ataxia Federation (FEDAES) d

Trunk sway in patients with spinocerebel
Trunk sway in patients with spinocerebellar ataxia
✍ Bart P.C. Van de Warrenburg; Maaike Bakker; Berry P.H. Kremer; Bastiaan R. Bloem 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 268 KB

## Abstract We investigated whether quantified measurements of trunk sway during stance and gait tests in patients with autosomal dominant spinocerebellar ataxia (SCA) could be a useful approach to assess ataxia, which is highly relevant for adequate follow‐up and future intervention studies. Exami

Predictors of progression in patients wi
Predictors of progression in patients with Friedreich ataxia
✍ Alison La Pean; Neal Jeffries; Chelsea Grow; Bernard Ravina; Nicholas A. Di Pros 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB

## Abstract Friedreich ataxia is an inherited, progressive, neurodegenerative disorder that is clinically heterogeneous. It is caused by a trinucleotide (GAA) repeat expansion resulting in frataxin loss and oxidative stress. We assessed clinical features including the development of cardiomyopathy