𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Short-term prophylaxis with cefuroxime in colorectal surgery for cancer

✍ Scribed by S. Colizza; S. De Fazio; A. Addari; R. Grande; G. Cucchiara

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
297 KB
Volume
35
Category
Article
ISSN
0022-4790

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✦ Synopsis

A controlled study of short-term prophylaxis with cefuroxime was performed on a group of 52 patients with colorectal neoplasms who underwent elective surgery. The patients were divided into two groups, A and B. Group A received the antibiotic immediately before surgery, intraincisionally and immediately after the end of operation; group B was treated only postoperatively. Each patient received a total of 5,250 mg of cefuroxime. Wound sepsis was demonstrated in 11.5% of cases of group A and 23.0% of group B (P<O.Ol); another type of sepsis was observed in 34% of group A and 11.5% of group B (P<O.OOl). There was no difference in the operative mortality in the two groups.

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