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Short term in vivo biocompatibility testing of biodegradable poly(D,L-lactide)—growth factor coating for orthopaedic implants

✍ Scribed by Britt Wildemann; Andre Sander; Philipp Schwabe; Martin Lucke; Ulrich Stöckle; Michael Raschke; Norbert P. Haas; Gerhard Schmidmaier

Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 441 KB
Volume: 26
Category: Article
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2004.10.004

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## Abstract Local application of growth factors like insulin like growth factor‐I (IGF‐I) and transforming growth factor‐beta 1 (TGF‐β1) from a biodegradable thin layer of poly(D,L‐lactide) (PDLLA) coated implants could stimulate fracture healing. A new “cold coating technique” for metallic implant