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Short-term exposure to transforming growth factor β induces long-term fibrotic responses

✍ Scribed by I. Michael Wormstone; Ian K. Anderson; Julie A. Eldred; Lucy J. Dawes; George Duncan

Book ID
116456510
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
702 KB
Volume
83
Category
Article
ISSN
0014-4835

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Transforming growth factor-(3 (TGF-p) niodulates growth and differentiation in many cell types and is abundant in bone matrix. We recently showed that human cord blood monocytes cultured in the presence of 1,25(OH),D, acquire some features of osteoclast precursors. Since TGF-P has been shown to infl