✦ LIBER ✦

Short-term estrogen test for cytodiagnosis in postmenopausal women

✍ Scribed by Masamichi Kashimura; Shinji Baba; Shuji Nakamura; Keita Matsukuma; Toshiharu Kamura

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 420 KB
Volume: 3
Category: Article
ISSN: 8755-1039
DOI: 10.1002/dc.2840030302

No coin nor oath required. For personal study only.

✦ Synopsis

A short-term estrogen test was used to obtain a correct cytologic diagnosis in 73 patients with an equivocal atrophic cellular pattern. Overestimation in cytodiagnosis was markedly eliminated. and the correct cytologic diagnosis was made in 81 % of the cell samples after the estrogen test. The purpose of this study was not only to confirm the usefulness of the short-term estrogen test, but also to observe the cytomorphologic changes before and after ihe test. Thick cytoplasm, vacuoles in the cytoplasm, and a distinct cell border increased, while the amorphous chromatin pattern was eliminated after the estrogen test. Maturation of atypical cells in cases of dysplasia, carcinoma in situ, and invasive squamous-cell carcinoma was investigated before and afrer the estrogen test. Although malignant cells were not injluenced by estrogen, maturation of dysplastic cells was induced after the test. Diagn Cytopathol

1987;3: 181-1 84.

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