## Abstract Bioartificial liver devices require membranes to support the function and viability of hepatocytes because they are anchorageโdependent cells. This study investigated the ability of several polymeric membranes to support the functions of primary hepatocyte cultures. Tailorโmade membrane
Short-term effects of chlorophenols on the function and viability of primary cultured rat hepatocytes
โ Scribed by Christiane Aschmann; Torsten Stork; Otmar Wassermann
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 621 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0340-5761
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The apparent kinetics of uptake of various model substrates were examined for hepatocytes in suspension and primary culture up to 72 h. The ability of hepatocytes to take up taurocholate and ouabain was decreased in culture. Vmax for uptake of both substrates diminished rapidly with increasing time
## Background It is well known that cytotoxic factors, such as lipopolysaccharides, derange nitrogen metabolism in hepatocytes and nitric oxide (NO) is involved among the other factors regulating this metabolic pathway. Hepatocytes have been shown to express large levels of NO following exposure to
The formation of intracellular lumina with apical differentiation is observed in several cancerous epithelial cell lines including human hepatocarcinoma. This disorder of cell polarization can be induced by the inhibition of cell-cell communication, a known factor of carcinogenesis. This work was d
## Abstract We have characterized the effect of the hepatomitogen epidermal growth factor (EGF) on the expression of the cellular protooncogenes cโHaโras and cโmyc in shortโterm (48 hours) primary hepatocyte culture. mRNA concentrations of both protooncogenes increased dramatically in nonproliferat