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Short-term effects of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor on cholesterol and bile acid synthesis in humans

โœ Scribed by Tadashi Yoshida; Akira Honda; Junichi Shoda; Masato Abei; Yasushi Matsuzaki; Naomi Tanaka; Hiroshi Miyazaki; Toshiaki Osuga


Book ID
107489476
Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
110 KB
Volume
32
Category
Article
ISSN
0024-4201

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3-hydroxy,3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors reduce biliary cholesterol saturation index (CSI) in duodenal bile in hypercholesterolemic patients and might be useful for gallstone dissolution. However, preliminary data suggest that these drugs are not effective in this respect