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Short-term course of 1,25(OH)2D3stimulates osteoblasts but not osteoclasts in osteoporosis and osteoarthritis

โœ Scribed by Piet Geusens; Dirk Vanderschueren; Anne Verstraeten; Jan Dequeker; Paul Devos; Roger Bouillon


Book ID
110554702
Publisher
Springer
Year
1991
Tongue
English
Weight
574 KB
Volume
49
Category
Article
ISSN
1432-0827

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The cytokine interleukin-6 (IL-6) was produced by neonatal mouse parietal bones during a 6- or 48-hour culture period in response to prostaglandin E2 (PGE2) and bovine parathyroid hormone (PTH) 1-34 fragment but not 1,25-dihydroxyvitamin D3 [1,25(OH)2D3]. At the same time there was an increase in ta