Hepatic steatosis increases the extent of cellular injury incurred during ischemia/reperfusion (I/R) injury. (-)-Epigallocatechin gallate (EGCG), the major flavonoid component of green tea (camellia sinensis) is a potent antioxidant that inhibits fatty acid synthase (FAS) in vitro. We investigated t
✦ LIBER ✦
Short-term administration of (−)-epigallocatechin gallate reduces hepatic steatosis and protects against hepatic ischemia/reperfusion injury in steatotic mice
✍ Scribed by Ryan N. Fiorini; Jennifer Donovan; David Rodwell III; Zachary Evans; John Markowitz; Michael G. Schmidt; Kenneth D. Chavin
- Book ID
- 119240990
- Publisher
- Springer-Verlag
- Year
- 2005
- Tongue
- English
- Weight
- 63 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1091-255X
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Hepatic ischemia/reperfusion (I/R) injury is very important in transplant surgery. To study the mechanism of receptor activator for nuclear factor kappa B-Fc (RANK-Fc) in protection against I/R injury, 90 male BALB/c mice were randomly divided into 3 groups: a phosphate-buffered saline (PBS) (sham)