Short tandem repeat (STR) locus HUMD8S306 in a large population sample from Germany
✍ Scribed by Dr. Mark Benecke; Manuela Knopf; Wolfgang Voll; Wolfgang Oesterreich; Yvonne Jacobi; Jeanett Edelmann
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 183 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0173-0835
No coin nor oath required. For personal study only.
✦ Synopsis
Short tandem repeat (STR) locus HUMDSS306 in a large population sample from Germany
Applied DNA typing in medico-legal investigations, in criminalistic practice, and in paternity cases often relies on high inclusion and exclusion probabilities. For that reason, the short autosomal tandem repeat locus D8D306 was validated for forensic use and incorporated into a nonoverlapping multiplex reaction with HUMDHFRP2 and HUMCD4. The allele frequencies of D8S306 in four different regions of Germany (n = 1220 alleles) were determined for use in a population database; the allele distributions did not significantly deviate from each other. The hererozygosity of D8S306 is 83 %, expected exclusion chance in stain cases is 96% (paternity cases: 69%), the lowest amount of sucessfully amplified DNA was 30 pg. The alleles are in Hardy-Weinberg equilibrium (exact test).