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Short noncoding DNA fragments improve the immune potency of electroporation-mediated HBV DNA vaccination

✍ Scribed by Peng, J; Shi, S; Yang, Z; Ding, Q; Hai, W; Tang, H; Yang, Y; Bernstein, J R; Peyda, P; Xu, Y


Book ID
126801721
Publisher
Nature Publishing Group
Year
2014
Tongue
English
Weight
1016 KB
Volume
21
Category
Article
ISSN
0969-7128

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## Abstract ## Background Many clinical trials show that DNA vaccine potency needs to be greatly enhanced. We have reported that the N‐terminal fragment of glycoprotein 96 (gp96) is able to produce an adjuvant effect for production of cytotoxic T‐lymphocytes (CTLs) with hepatitis B virus (HBV)‐spe