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Short hairpin RNA induces methylation of hepatitis B virus covalently closed circular DNA in human hepatoma cells

โœ Scribed by Park, Hyun Kyung; Min, Bo Young; Kim, Nam Young; Jang, Eun Sun; Shin, Cheol Min; Park, Young Soo; Hwang, Jin-Hyeok; Jeong, Sook-Hyang; Kim, Nayoung; Lee, Dong Ho; Kim, Jin-Wook


Book ID
121192031
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
808 KB
Volume
436
Category
Article
ISSN
0006-291X

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Evidence that methylation of hepatitis B
โœ Yanhai Guo; Yongnian Li; Shijie Mu; Ju Zhang; Zhen Yan ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 128 KB ๐Ÿ‘ 1 views

## Abstract Epigenetic factors may modulate chronic Hepatitis B viral infection by affecting virion gene transcription. The aim of this study was to compare the methylation status of the intrahepatic covalently closed circular DNA (cccDNA) CpG island 2 and HBV replication capability. HBV cccDNA was