Short convergent route to homochiral carbocyclic-2?-deoxynucleosides and carbocyclic ribonucleosides
β Scribed by Biggadike, Keith; Borthwick, Alan D.; Exall, Anne M.; Kirk, Barrie E.; Roberts, Stanley M.; Youds, Peter
- Book ID
- 120641048
- Publisher
- The Royal Society of Chemistry
- Year
- 1987
- Tongue
- English
- Weight
- 174 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0022-4936
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A series of chirat 2-substituted-carbocyclic-NECA analogs was prepared in seven steps with an efficient resolution. The overall yield is good and can be applied to the other carbocyclic nucleosides. Adenosine is a potent coronary vasodilator, at first described by Drury and Szent-Gyorgyi in 1929' .