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Short chemoenzymatic synthesis ofS-enantiomers of two systemic fungicides

✍ Scribed by Maja Majerić; Amir Avdagić; Zdenko Hameršak; Vitomir Šunjić


Book ID
104633040
Publisher
Springer Netherlands
Year
1995
Tongue
English
Weight
356 KB
Volume
17
Category
Article
ISSN
0141-5492

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Based on the lipase-catalysed kinetic resolution of the silyloxyalcohol (1RS,2SR)-5 by transesterification with vinyl acetate in the presence of lipase from Pseudomonas cepacia a synthesis of both enantiomers of the ~-amino acid cispentacin (1R,2S)-I and (1S,2R)-I using simple functional group inter