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Short and Efficient Approach Towards Buxozine-C, an Alkaloid from Buxus sempervirens

✍ Scribed by Hai-Feng Liu; Min Ji; Jin Cai


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
219 KB
Volume
339
Category
Article
ISSN
0365-6233

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✦ Synopsis


Abstract

Buxus alkaloids display a wide range of interesting pharmacological activities. Here, we present a short and efficient approach towards one of the alkaloids, buxozine‐C. The first synthesis has been achieved with 91% yield starting from cyclovirobuxine‐D by forming a tetrahydro‐oxazine ring with formaldehyde at room temperature.


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