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SHMT11420 andMTHFR677 variants are associated with rectal but not colon cancer

✍ Scribed by Viktor Komlósi; Erika Hitre; Éva Pap; Vilmos Adleff; Andrea Réti; Éva Székely; Anna Bíró; Péter Rudnai; Bernadette Schoket; Judit Müller; Béla Tóth; Szabolcs Ottó; Miklós Kásler; Judit Kralovánszky; Barna Budai

Book ID
115010216
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
274 KB
Volume
10
Category
Article
ISSN
1471-2407

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## Abstract Glutathione peroxidases (GPXs) are selenium‐dependent enzymes that reduce and, thus, detoxify hydrogen peroxide and a wide variety of lipid hydroperoxides. We investigated tagSNPs in __GPX1‐4__ in relation to colorectal neoplasia in three independent study populations capturing the rang