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Shiquandabutangjiaweibang inhibits tumor metastasis and angiogenesis via regulation of topoisomerase-1

✍ Scribed by Sung Hoon Kim; Tae-Hyung Lee; Deok-Chun Yang; Hyung-Min Kim; Jeung-Beum Kim; Mi-Kyung Park; Yong-Soo Bae

Book ID
116642548
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
190 KB
Volume
98
Category
Article
ISSN
0378-8741

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The immunosuppressant FTY720 inhibits tu
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## Abstract FTY720, a sphingosine 1‐phosphate (S1P) analog, acts as an immunosuppressant through trapping of T cells in secondary lymphoid tissues. FTY720 was also shown to prevent tumor growth and to inhibit vascular permeability. The MTT proliferation assay illustrated that endothelial cells are