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SHIP2 controls PtdIns(3,4,5)P3 levels and PKB activity in response to oxidative stress

✍ Scribed by Jing Zhang; Zhenan Liu; Joanne Rasschaert; Daniel Blero; Laurence Deneubourg; Stéphane Schurmans; Christophe Erneux; Xavier Pesesse


Book ID
113528112
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
754 KB
Volume
19
Category
Article
ISSN
0898-6568

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✍ Christophe Erneux; William's Elong Edimo; Laurence Deneubourg; Isabelle Pirson 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 696 KB

## Abstract The SH2 domain containing inositol 5‐phosphatase 2 (SHIP2) belongs to the family of the mammalian inositol polyphosphate 5‐phosphatases. The two closely related isoenzymes SHIP1 (or SHIP) and SHIP2 contain a N‐terminal SH2 domain, a catalytic domain, potential PTB domain‐binding sites (