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Shikonin suppresses ERK 1/2 phosphorylation during the early stages of adipocyte differentiation in 3T3-L1 cells

โœ Scribed by Gwon, So; Ahn, Ji; Jung, Chang; Moon, Bo; Ha, Tae


Book ID
121628739
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
686 KB
Volume
13
Category
Article
ISSN
1472-6882

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A mouse cell line 3T3-L1 is differentiated into adipocytes when treated with an inducer cocktail (IDX) (insulin, dexametahsone, and a cAMP phosphodiesterase inhibitor of isobutyl-methylxanthine (IBMX)). Here, we report that PLD1, but not PLD2, mRNA and protein increased during the early differentiat