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Shiga toxin B-subunit binds to the chaperone BiP and the nucleolar protein B23

✍ Scribed by Thomas Falguières; Ludger Johannes


Book ID
119980487
Publisher
Portland Press
Year
2006
Tongue
English
Weight
442 KB
Volume
98
Category
Article
ISSN
0248-4900

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✍ Benoit Vingert; Olivier Adotevi; Delphine Patin; Steffen Jung; Protul Shrikant; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 438 KB 👁 1 views

## Abstract The non‐toxic B‐subunit of Shiga toxin (STxB) interacts with the glycolipid Gb~3~, which is preferentially expressed on dendritic cells (DC) and B cells. After administration of STxB chemically coupled to OVA (STxB‐OVA) in mice, we showed that the immunodominant OVA~257–264~ peptide res