## Objective: To determine the impact of type ii collagen (cii)-reactive t cells on the production of chemokines in the joints of patients with rheumatoid arthritis (ra). ## Methods: T cell proliferative responses to bovine cii were assayed in synovial fluid (sf) mononuclear cells and peripheral
✦ LIBER ✦
Shift toward T helper 1 cytokines by type II collagen–reactive T cells in patients with rheumatoid arthritis
✍ Scribed by Sung-Hwan Park; Do-June Min; Mi-La Cho; Wan-Uk Kim; Jeehee Youn; Won Park; Chul-Soo Cho; Ho-Youn Kim
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 117 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective In reactive arthritis (ReA), a bacteria‐specific T cell response to the triggering microbe is detected in synovial fluid. So far, direct characterization of bacteria‐specific T cells and identification of the immunodominant fine specificities remain difficult due to the la