Latent TGF-β1 activation by platelets
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Robert Blakytny; Anna Ludlow; Gail E.M. Martin; Grenham Ireland; Leif R. Lund; M
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Article
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2004
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John Wiley and Sons
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English
⚖ 362 KB
Platelets are a major source of transforming growth factor-beta1 (TGF-beta1) in the circulation as they release latent growth factor in response to activation. We report here that human platelets, when stimulated with thrombin, activated a significant proportion of the latent TGF-beta released. Late