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Shear Stress-Induced Nitric Oxide Release Triggers the Liver Regeneration Cascade

✍ Scribed by Jodi M. Schoen; H.Helen Wang; Gerald Y. Minuk; W.Wayne Lautt


Book ID
115642147
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
146 KB
Volume
5
Category
Article
ISSN
1089-8603

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Increased nitric oxide (NO) release has been implicated in the pathogenesis of the hyperdynamic circulation in portal hypertension. NOS 3 (eNOS) causes NO release from the endothelium in response to physical stimuli, such as increased blood flow and shear stress. We evaluated the functional activity