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Shear stress activation of nitric oxide synthase and increased nitric oxide levels in human red blood cells

✍ Scribed by Pinar Ulker; Nazmi Yaras; Ozlem Yalcin; Ciler Celik-Ozenci; Paul C. Johnson; Herbert J. Meiselman; Oguz K. Baskurt


Book ID
116790883
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
626 KB
Volume
24
Category
Article
ISSN
1089-8603

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In the present study we examined the effect of oxidative stress-mediated hydroperoxide formation on the activity of nitric oxide synthase (NOS) in retinal cells in culture. Oxidative stress was induced in the presence of Fe 2Ψ‰ and ascorbate or Fe 2Ψ‰ alone and compared to H 2 O 2 -induced maximal cel