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Shear-induced platelet activation and platelet microparticle formation in native human blood

✍ Scribed by Kjell S. Sakariassen; Pl A. Holme; Una Ørvim; R. Marius Barstad; Nils O. Solum; Frank R. Brosstad

Book ID
117258956
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
879 KB
Volume
92
Category
Article
ISSN
0049-3848

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Fluid shear stress has been known to activate platelet reaction such as aggregation, but the exact mechanism of shear-induced platelet aggregation (SIPA) has not been fully understood. Calpain, an intracellular calcium-activated cysteine protease, is abundant in platelets and is considered to be act