Shaping a Morphogen Gradient for Positional Precision
β Scribed by He, Feng; Saunders, Timothy E.; Wen, Ying; Cheung, David; Jiao, Renjie; Rein ten Wolde, Pieter; Howard, Martin; Ma, Jun
- Book ID
- 119207346
- Publisher
- Biophysical Society
- Year
- 2010
- Tongue
- English
- Weight
- 543 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0006-3495
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Gradients of cellular activities are ubiquitous in embryonic development. It is widely believed that the inhomogeneous spatial distribution of a morphogen would be able to set up such gradients. But how then does the morphogen propagate in the first place? Straightforward molecular diffusion is ofte
## Background One way in which positional information is established during embryonic development is through the graded distribution of diffusible morphogens. Unfortunately, little is known about how cells interpret different concentrations of morphogen to activate different genes or how thresholds