Shape and accessible surface area of globular proteins
โ Scribed by Ronald E. Gates
- Book ID
- 118918107
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 507 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0022-2836
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๐ SIMILAR VOLUMES
Results are presented for proteins with known three-dimensional structure (lysozyme, myoglobin, ribonuclease), which show that the probability of label incorporation upon bombardment by "hot" tritium atoms may be quantitatively linked with the surface area of the protein accessible to water molecule
Globular proteins fold into compact particles with interior amino acid residues shielded from the surrounding aqueous environment. An early hypothesis holds that entropic hydrophobic forces drive this phenomenon. However, previous analyses based on a binary description of the accessible surfaces of