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SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes

✍ Scribed by T. Sasaoka; H. Hori; T. Wada; M. Ishiki; T. Haruta; H. Ishihara; M. Kobayashi

Book ID
105822582
Publisher
Springer
Year
2001
Tongue
English
Weight
256 KB
Volume
44
Category
Article
ISSN
0012-186X

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✍ Annemarie Gagnon; Yulia Artemenko; Thet Crapper; Alexander Sorisky 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB

## Abstract The role of the inositol lipid 5‐phosphatase (SHIP2) in preadipocyte signaling is not known. Although overexpression of SHIP2 inhibited proliferation and ^3^H‐thymidine incorporation in 3T3‐L1 preadipocytes, there was no effect on insulin‐induced adipogenesis. Insulin promoted SHIP2 tyr