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SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas

✍ Scribed by Waha, A; Koch, A; Hartmann, W; Milde, U; Felsberg, J; Hübner, A; Mikeska, T; Goodyer, C G; Sörensen, N; Lindberg, I


Book ID
110072336
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
357 KB
Volume
26
Category
Article
ISSN
0950-9232

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## Abstract Pharmacological demethylation‐based gene expression profile analysis is a useful tool to identify epigenetically silenced tumour suppressor genes. __HGF activator inhibitor 2 (HAI‐2)__, a serine protease inhibitor, has been identified as one of the candidate tumour suppressor genes in h