6/155), high white cell number (13/155) (red cell unit) or low thrombocyte number (14/125) (thrombocyte unit). Summary: Donors with low hemoglobin levels have to be excluded from the blood donation service for 3 months. So, in theory haemoglobin concentration of all total blood units is suitable for
sFRP1 promoter methylation is associated with persistent Philadelphia chromosome in chronic myeloid leukemia
✍ Scribed by Melek Pehlivan; Zeynep Sercan; Hakkı Ogun Sercan
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 390 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0145-2126
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## Abstract ## BACKGROUND Significantly elevated telomerase activity (TA) has been found in samples from patients with many malignant hematologic diseases. However, the impact of elevated TA on the course of patients with chronic phase chronic myeloid leukemia (CP‐CML) is unknown. ## METHODS Usi
## Abstract ## BACKGROUND. Clonal cytogenetic abnormalities (CCA) were detected in Philadelphia chromosome (Ph)‐negative cells in some patients with chronic myeloid leukemia (CML) who attained a cytogenetic response to imatinib mesylate. In some patients, CCA/Ph‐negative status was associated with
Chronic myeloid leukemia (CML) patients with persistent or relapsed disease following bone-marrow transplantation (BMT) usually show both clonal and non-clonal cytogenetic changes in addition to the Philadelphia (Ph) translocation. These changes are presumably due to conditioning prior to transplant