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Sezary syndrome in a patient with multiple myeloma: demonstration of a clonally distinct second malignancy

✍ Scribed by G. Cartron; Ph. Roingeard; L. Benboubker; L. Vaillant; S. Tartas; M. Delain; T. Lefranc; J. L. Brémond; M. Bout; C. Linassier; Ph. Colombat


Book ID
114792505
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
539 KB
Volume
63
Category
Article
ISSN
0902-4441

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We describe a patient who presented with a neutrophilic leukocytosis, normal karyotype, and IgA multiple myeloma. One year after diagnosis she developed diffuse myelofibrosis as well as multiple lytic lesions of bone. Given the myeloproliferative features of her case, the clonality of her peripheral