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Sex specific response of cultured human bone cells to ERα and ERβ specific agonists by modulation of cell proliferation and creatine kinase specific activity

✍ Scribed by Dalia Somjen; Sara Katzburg; Orli Sharon; Esther Knoll; David Hendel; Naftali Stern


Book ID
116698666
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
388 KB
Volume
125
Category
Article
ISSN
0960-0760

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## Abstract In cultured human osteoblasts estradiol‐17β (E2) modulated DNA synthesis, the specific activity of creatine kinase BB (CK), 12 and 15 lipoxygenase (LO) mRNA expression and formation of 12‐ and 15‐hydroxyeicosatetraenoic acid (HETE). We now investigate the response of human bone cell lin