Sex, neural tube defects, and multisite closure of the human neural tube
β Scribed by Seller, Mary J.
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 545 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract **BACKGROUND**: The number of mouse mutants and strains with neural tube closure defects (NTDs) now exceeds 190, including 155 involving known genes, 33 with unidentified genes, and eight βmultifactorialβ strains. **METHODS**: The emerging patterns of mouse NTDs are considered in relati
Neural tube closure (neurulation) is a complex process involving many cell phenomena. Both extrinsic and intrinsic forces are essential to elevate the neural plate into the neural folds and to bring the folds into apposition for closure. Extrinsic forces involve the underlying mesenchyme cells and e
Epidemiologic studies have established clear variations in the occurrence of neural tube defects (NTDs) associated with demographic and other factors. Methods of counting NTD-affected pregnancies and other birth defects rely on multiple sources of information such as hospital records and birth certi
Neural tube defects are a complex, heterogeneous, and multifactorial group of disorders. In humans it is estimated that 80% of neural tube defects are ''multifactorial'' and are influenced by both genetic and environmental factors. It appears that 70% of neural tube defects in humans are related to