## Abstract Osteopontin (OPN), a secreted phosphoprotein involved in immune regulation and bone homeostasis, is a major component of bone, the natural habitat of longβlived plasma cells and multiple myeloma (MM). We show that only some MM cell lines and primary patient samples express OPN at high l
β¦ LIBER β¦
Sex hormones and immune dysregulation in multiple myeloma
β Scribed by Hele Everaus; Jane Lehtmaa
- Book ID
- 105295185
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 532 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0340-7004
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Multiple myeloma (MM) is a B-cell lymphoid malignancy suspected to be associated with immunologic factors. Given recent findings associating single-nucleotide polymorphisms (SNPs) in innate immunity genes with non-Hodgkin lymphoma, we conducted an investigation of innate immune gene variants using s