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Sex hormones affect the production of recombinant Factor IX in CHO and HEK-293 cell lines

✍ Scribed by Nazanin Dadehbeigi; Seyed Nasser Ostad; Mohammad Ali Faramarzi; Mohammad Hossein Ghahremani


Publisher
Springer Netherlands
Year
2008
Tongue
English
Weight
235 KB
Volume
30
Category
Article
ISSN
0141-5492

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## Abstract Mammalian cell lines are currently employed as one of the main cellular factories for the expression of recombinant protein‐based drugs. The establishment of high‐producing cell lines typically begins with a heterogeneous starter population of cells, from which the highest producing cel