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Sex hormones affect the production of recombinant Factor IX in CHO and HEK-293 cell lines

✍ Scribed by Nazanin Dadehbeigi; Seyed Nasser Ostad; Mohammad Ali Faramarzi; Mohammad Hossein Ghahremani

Publisher: Springer Netherlands
Year: 2008
Tongue: English
Weight: 235 KB
Volume: 30
Category: Article
ISSN: 0141-5492
DOI: 10.1007/s10529-008-9774-6

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## Abstract Mammalian cell lines are currently employed as one of the main cellular factories for the expression of recombinant protein‐based drugs. The establishment of high‐producing cell lines typically begins with a heterogeneous starter population of cells, from which the highest producing cel