Sex hormone modulation of autoimmunity i
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Jirayr Roubinian; Norman Talal; Pentti K. Siiteri; Jacqueline A. Sadakian
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Article
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1979
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John Wiley and Sons
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English
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## Abstract Prepubertal castration of female NZB/NZW (B/W) hybrid mice did not influence mortality, whereas prepubertal castration of male B/W mice caused premature death and enhanced autoantibody formation. Prepubertal castration combined with the administration of sustained estradiolβ17βΞ² (Eβ2) e