The administration of the GABA-blocking agents picrotoxin and bicuculline to adult (2.5-3 months old) CBA/HZgr mice resulted in the appearance of convulsions, the occurrence and/or lethality of which was greater in males than in females. The latency of picrotoxin-induced convulsions was also shorter
✦ LIBER ✦
Sex differences in the response to GABA antagonists depend on the route of drug administration
✍ Scribed by Danka Peričić; Maja Bujas
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 95 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0014-4819
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