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Sex differences in the proportion of esophageal squamous cell carcinoma cases attributable to tobacco smoking and alcohol consumption

✍ Scribed by Pandeya, Nirmala; Olsen, Catherine M.; Whiteman, David C.

Book ID: 123094496
Publisher: Elsevier
Year: 2013
Tongue: English
Weight: 243 KB
Volume: 37
Category: Article
ISSN: 1877-7821
DOI: 10.1016/j.canep.2013.05.011

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## Abstract Genetic variants in alcohol dehydrogenase‐1B (__ADH1B__) and aldehyde dehydrogenase‐2 (__ALDH2__) genes modulate acetaldehyde removal upon alcohol ingestion. Although these genetic vulnerabilities have been linked to higher esophageal squamous cell carcinoma (ESCC) risks, it is unclear