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Sex differences in sulfation and glucuronidation of phenol, 4-nitrophenol and N-hydroxy-2-acetylaminofluorene in the rat in vivo

โœ Scribed by John H.N. Meerman; Chris Nijland; Gerard J. Mulder


Book ID
117979883
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
417 KB
Volume
36
Category
Article
ISSN
0006-2952

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In a previous study, we found that treating transgenic Big Blue rats with the hepatocarcinogen N-hydroxy-2-acetylaminofluorene (N-OH-AAF) produced the same major DNA adduct in the target liver and the nontarget spleen lymphocytes and bone marrow cells, induced lacI mutants in the liver, and induced